RX 6600 vs GTX 1080 Ti
GTX 1080 Ti
$445.00 new
$159.00 used on eBay
See GTX 1080 Ti price on Amazon → See used listings on eBay →Price difference: $150.00 (25.2%) — the GTX 1080 Ti is cheaper. Used gap: $91.00 .
Specs compared
| Spec | RX 6600 | GTX 1080 Ti |
|---|---|---|
| Memory | 8 GB | ★ 11 GB |
| Memory type | GDDR6 | GDDR5X |
| Boost clock | ★ 2491 MHz | 1582 MHz |
| Core clock | — | — |
| TDP | ★ 132 W | 250 W |
| Interface | PCIe 4.0 | PCIe 3.0 |
| Length | — | — |
| New price | $595.00 | $445.00 ★ |
| Used price (eBay) | $250.00 | $159.00 |
★ indicates the better value for that spec.
Verdict
With the RX 6600 running 25% above the GTX 1080 Ti — a $150.00 premium — the two cards sit in meaningfully different price brackets. The GTX 1080 Ti wins on value unless the extra performance matters for your workload.
Power consumption is a meaningful differentiator here: the RX 6600 draws 132 W versus 250 W for the GTX 1080 Ti. That 118 W gap can determine whether your existing PSU is sufficient and will show up in long-term electricity costs.
As an NVIDIA card, the GTX 1080 Ti gives you access to DLSS 4 super-resolution and Frame Generation, which can meaningfully lift frame rates in supported titles. The RX 6600 counters with FSR 4, which is open-source and works across a wider range of games — including some that don't support DLSS. Which ecosystem matters more depends on the games in your library.
For most buyers at this price point, the GTX 1080 Ti is the practical choice — unless DLSS or a large VRAM advantage specifically matters to your use case.
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Prices as of October 15, 2026. Updated daily.