RX 580 vs RX 6600
Price difference: $335.01 (56.3%) — the RX 580 is cheaper. Used gap: $171.00 .
Specs compared
| Spec | RX 580 | RX 6600 |
|---|---|---|
| Memory | 8 GB | 8 GB |
| Memory type | GDDR5 | GDDR6 |
| Boost clock | 1340 MHz | ★ 2491 MHz |
| Core clock | — | — |
| TDP | 185 W | ★ 132 W |
| Interface | PCIe 3.0 | PCIe 4.0 |
| Length | — | — |
| New price | $259.99 ★ | $595.00 |
| Used price (eBay) | $79.00 | $250.00 |
★ indicates the better value for that spec.
Verdict
With the RX 6600 running 56% above the RX 580 — a $335.01 premium — the two cards sit in meaningfully different price brackets. The RX 580 wins on value unless the extra performance matters for your workload.
Unless you specifically need what the RX 6600 offers, the RX 580 is the stronger value at this price gap.
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Prices as of October 15, 2026. Updated daily.